Titel: Human Breast Milk Bank Frankfurt – Experience after 1369 bottles of delivered donor human breast milk
ID: PS-15-2
Art: Poster
ePoster-Session 2 – PS-2: Blutspende und Donormanagement | PS-3: Versorgungsforschung | PS-15: Zukunftsgebiete der Transfusionsmedizin

Referent: Veronika Brixner (Frankfurt)

Abstract - Text

Offenlegung Interessenkonflikt:



Based on the recommendations for promoting human milk banks in Germany, Austria, and Switzerland (EFCNI) we analyzed donated human breast milk and it's processing via pasteurization for the first 12 months of donor recruitment. We produced 84 batches of pooled and pasteurized human breast milk, using a single donor strategy. Each donor was screened before and after the donation period to exclude possible detectable infectious diseases. We stored one bottle of each batch as a retain sample and at least one bottle per batch was tested for bacterial contamination, fat, protein, lactose, somatic cells and freezing point. If the results of this analysis were within specification the pasteurized milk was released for feeding.


We received 200 liters of human breast milk from 18 healthy voluntary unpaid donors who gave birth to premature babies. In total we supported 34 premature babies with 1369 bottles of pasteurized donor breast milk with either approx. 50ml or 100ml, including twins and triplets and preterm infants with a birth weight below 500g.

All fed batches of milk were free of bacterial contamination and displayed an average pH value of 6.8. On average, the pasteurized human breast milk contained 3.56 % fat, 1.24% protein and 6.87% lactose. The mean freezing point was at -0.546 °C and the mean somatic cell content was 24685 cells/ml.


The World Health Organization rates human milk as the most adequate nutrition, especially for preterm and ill infants; if their mother"s milk is not available quality-controlled donor milk is highly recommended. Various studies pointed out that breast milk reduces the risk of necrotizing enterocolitis (NEC), a life threatening inflammatory bowel disorder and sepsis. Furthermore it constitutes to the neural development of the premature infant and their digestive and immune system.


The idea of establishing a human milk bank within a blood donation service in cooperation with the department of neonatology at a hospital is ideal due to many synergetic effects, e.g. the experience in standardized donor screening for infectious diseases in a blood bank and the expertise in medical treatment of preterm infants at the hospital. Analysis of one year of human milk processing demonstrated the achievability of producing a high quality product within a blood donation service.