Session

05.02.2019     10:45–12:15

Title:
Workshop 4: Stem Cell Features in Cancer
Type:
Workshop Sessions
10:45- 11:15 Prof Andreas Trumpp (DKFZ and HI-STEM, Heidelberg)

Title: Introduction and Examples for Stem Cell Features in Cancer
11:15-11:45 Prof. Carsten Müller Tidow (Medizinische Klinik V, Hämatologie, Onkologie, Rheumatologie Universitätsklinikum Heidelberg)

Title: Stem Cells and Therapy Resistance
11:45-11:55 Prof. Thomas Brabletz (Experimental Medicine I, Nikolaus-Fiebiger-Center for Molecular Medicine
University Erlangen-Nuernberg)

Title: Overview: Epithelial-Mesenchymal Transition (EMT) and Stemness
11:55-12:15 Discussion with the speakers

05.02.2019
10:45–12:15

Title:
Workshop 4: Stem Cell Features in Cancer
Type:
Workshop Sessions
10:45- 11:15 Prof Andreas Trumpp (DKFZ and HI-STEM, Heidelberg)

Title: Introduction and Examples for Stem Cell Features in Cancer
11:15-11:45 Prof. Carsten Müller Tidow (Medizinische Klinik V, Hämatologie, Onkologie, Rheumatologie Universitätsklinikum Heidelberg)

Title: Stem Cells and Therapy Resistance
11:45-11:55 Prof. Thomas Brabletz (Experimental Medicine I, Nikolaus-Fiebiger-Center for Molecular Medicine
University Erlangen-Nuernberg)

Title: Overview: Epithelial-Mesenchymal Transition (EMT) and Stemness
11:55-12:15 Discussion with the speakers



Stem Cell Features in Cancer
Andreas Trumpp (Heidelberg)


Stem cells are essential for maintaining and repairing regenerative tissues in response to stress such as inflammation, infection or massive cell loss for example as a result of chemotherapy. However, genetic alterations of stem cells can lead to the generation of “cancer stem cells” (CSCs) that drive tumorigenesis and metastasis. This lecture will provide an overview about stem cell features and how these are involved in tumor initiation, tumor maintenance, metastasis and therapy resistance.