Programmpunkt

12:10

Titel: Impact of TTVR on Reverse Remodeling of Right-Ventricular function and morphology in patients with severe tricuspid regurgitation- a CMRI pilot study
Art: Abstractvortrag
Redezeit: 10 min
Session: Vorträge II (beste Abstracts)
Vorträge II (beste Abstracts)

Referent: Yoann Primet (Erfurt/DE)


Abstract - Text

Abstract-Text (inkl. Referenzen und Bildunterschriften)

Background: Tricuspid regurgutation (TR) is recognized as major public health concern with significant impact on morbidity and mortality. Multiple innovatie approaches fot transcatheter tricuspid valve repair (TTVR) are currently under development, however their impact on cardiac function and outcome is still unclear. Cardiac Magnetic Resonance Imaging (CMRI) is considered as reference technique for the right ventricular (RV) volumetric and functional measurements. Therefore, the purpose of the present study was to evaluate the impact of TTVR with the TriClip- Technique on CMRI-measured RV function and morphology.



Methods and Results:
Pre and post procedural to TTVR, RV function and morphology were evaluated in CMRI. Clinical outcome and quality of life were evaluated based on New York Heart Association (NYHA) class and the KCCQ-Score at baseline and within 30 days after Tri-clip Implantation.
In total, 17 patients underwent pre and post procedural CMRI. Mean age was 76,2 ±0.5 years, with 41.2% of male (n=7). All patients presented functional TR. Mean RV end-diastolic volume (RVEDV) and RV end-systolic volume (RVESV) at baseline were 189,1ml ±25.85ml and 96,5ml ±0.51ml, RV stroke volume (RVSV) was 92,6ml and the RV ejection fraction (RVEF) was 49.1%.



After a mean follow-up of 19.6 ±1.1d, RVEDV and RVESV had decreased to 179,5ml ±0.01ml and 84,7 ml ±5.95ml, respectively. The RVSV and RVEF increased to 94.8ml ±8.15ml and 53% ±0.14%, respectively. The quality of life evaluation showed an improvement of KCCQ-Score in 14/17 patients and remained unchanged or worsened in 3/17 patients.